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MEDU-27. ENHANCING SELUMETINIB-MEDIATED KILLING OF SHH MEDULLOBLASTOMA
Medulloblastoma (MB) is the most common primary malignant pediatric brain cancer with at least 5 distinct molecular subgroups. Of these subgroups, Sonic Hedgehog (SHH) MB exhibits extensive cellular heterogeneity, increased SHH signaling, and has an intermediate prognosis. Consequently, improved che...
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| Veröffentlicht in: | Neuro Oncol |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6477324/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.186 |
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