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EXTH-28. ENHANCING SELUMETINIB-MEDIATED KILLING OF SHH MEDULLOBLASTOMA
Medulloblastoma (MB) is the most common primary malignant pediatric brain cancer and consists of at least 5 distinct molecular subgroups. Of these subgroups, Sonic Hedgehog (SHH) MB exhibits extensive cellular heterogeneity, increased SHH signaling, and has an intermediate prognosis. Treatment strat...
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| Publicado en: | Neuro Oncol |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6217256/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.377 |
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