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EXTH-28. ENHANCING SELUMETINIB-MEDIATED KILLING OF SHH MEDULLOBLASTOMA

Medulloblastoma (MB) is the most common primary malignant pediatric brain cancer and consists of at least 5 distinct molecular subgroups. Of these subgroups, Sonic Hedgehog (SHH) MB exhibits extensive cellular heterogeneity, increased SHH signaling, and has an intermediate prognosis. Treatment strat...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Guppy, Brent, Liang, Lisa, Porter, Chris, Werbowetski-Ogilvie, Tamra
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217256/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.377
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