PDTM-28. THE CONTRIBUTION OF PAX GENES AS NOVEL TUMOR SUPPRESSORS IN GROUP 3 MEDULLOBLASTOMA

Medulloblastoma (MB) is the most common malignant primary pediatric brain tumor. Of the four distinct molecular MB subgroups, Group 3 MB has the worst prognosis, is highly metastatic, and is poorly defined with regard to the pathways that contribute to tumor progression. OTX2 is overexpressed/amplif...

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Bibliographic Details
Published in:Neuro Oncol
Main Authors: Zagozewski, Jamie, Morrison, Ludivine, Stromecki, Margaret, Palidwor, Gareth, Ramaswamy, Vijay, Werbowetski-Ogilvie, Tamra
Format: Artigo
Language:Inglês
Published: Oxford University Press 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217684/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.869
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