MEDU-19. EZH2-REGULATED INHIBITION OF HIPK2 SUPPRESSES TREATMENT-INDUCED APOPTOSIS IN GROUP 3 MEDULLOBLASTOMA

Our previous studies have shown that the epigenetic developmental regulator EZH2 is overexpressed in medulloblastoma (MB). EZH2 is known to repress developmental genes in embryonic stem cells to maintain their stem cell characteristics. To identify the role of EZH2 in medulloblastoma, we overexpress...

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Publicado en:Neuro Oncol
Autores principales: Sola, Ismail, Fosmire, Susan, Venkataraman, Sujatha, Balakrishnan, Ilango, Birks, Diane, Pierce, Angela, Foreman, Nicholas K, Vibhakar, Rajeev
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2019
Materias:
Medulloblastoma
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477235/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.178
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