MEDU-19. EZH2-REGULATED INHIBITION OF HIPK2 SUPPRESSES TREATMENT-INDUCED APOPTOSIS IN GROUP 3 MEDULLOBLASTOMA

Our previous studies have shown that the epigenetic developmental regulator EZH2 is overexpressed in medulloblastoma (MB). EZH2 is known to repress developmental genes in embryonic stem cells to maintain their stem cell characteristics. To identify the role of EZH2 in medulloblastoma, we overexpress...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Sola, Ismail, Fosmire, Susan, Venkataraman, Sujatha, Balakrishnan, Ilango, Birks, Diane, Pierce, Angela, Foreman, Nicholas K, Vibhakar, Rajeev
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Medulloblastoma
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477235/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.178
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