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MBRS-22. EZH2 OVEREXPRESSION INCREASES THE ONCOGENIC CHARACTER OF CEREBELLAR PROGENITORS AND ISOGRAFTS IN MICE RESULT IN TUMORS RESEMBLING GROUP 3 MEDULLOBLASTOMA
Previous studies have shown that EZH2, an epigenetic developmental regulator, is overexpressed in medulloblastoma. EZH2 is known to repress developmental genes in embryonic stem cells to maintain their stem cell characteristics. To identify the transcriptional networks that may be driving medullobla...
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| Publicat a: | Neuro Oncol |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6012260/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.467 |
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