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MEDU-16. MYC BUT NOT MYCN GENERATES AGGRESSIVE GROUP 3 MEDULLOBLASTOMA THROUGH ARF SUPPRESSION
Group 3 medulloblastoma (MB) carry the worst prognosis of all MB. The transcription factors MYC and MYCN are suggested drivers for a subset of these tumours; with MYC amplifications (17–20%) representing the most common genetic alteration in Group 3 tumours, while MYCN amplifications (4–6%) are less...
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| Veröffentlicht in: | Neuro Oncol |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6477231/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.175 |
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