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TMOD-38. GMYC: A NOVEL INDUCIBLE TRANSGENIC MODEL OF GROUP 3 MEDULLOBLASTOMA
Group 3 medulloblastoma (MB) carry the worst prognosis of all MB. The transcription factors MYC and MYCN have been suggested drivers for a subset of these tumors, with MYC amplifications (17–20%) representing the most common genetic alteration in Group 3 tumors, while MYCN amplifications (4–6%) are...
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| Udgivet i: | Neuro Oncol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6216757/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.1150 |
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