TMOD-38. GMYC: A NOVEL INDUCIBLE TRANSGENIC MODEL OF GROUP 3 MEDULLOBLASTOMA

Group 3 medulloblastoma (MB) carry the worst prognosis of all MB. The transcription factors MYC and MYCN have been suggested drivers for a subset of these tumors, with MYC amplifications (17–20%) representing the most common genetic alteration in Group 3 tumors, while MYCN amplifications (4–6%) are...

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Bibliographic Details
Published in:Neuro Oncol
Main Authors: Rosén, Gabriela, Weishaupt, Holger, Mainwaring, Oliver, Swartling, Fredrik
Format: Artigo
Language:Inglês
Published: Oxford University Press 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216757/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.1150
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