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TMOD-05. MYCN OVEREXPRESSION AND STABILIZATION DRIVES MEDULLOBLASTOMA FROM HUMAN NEURO-EPITHELIAL STEM CELLS
Medulloblastoma (MB) constitutes the most common malignant brain tumor in children. MB is divided into distinct molecular subgroups (WNT, SHH, Group 3 and Group 4) with different associated molecular profiles and prognoses. MYC gene family members are often overexpressed and/or amplified in all MB s...
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| Veröffentlicht in: | Neuro Oncol |
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| Hauptverfasser: | , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5692857/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.1044 |
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