TMOD-05. MYCN OVEREXPRESSION AND STABILIZATION DRIVES MEDULLOBLASTOMA FROM HUMAN NEURO-EPITHELIAL STEM CELLS

Medulloblastoma (MB) constitutes the most common malignant brain tumor in children. MB is divided into distinct molecular subgroups (WNT, SHH, Group 3 and Group 4) with different associated molecular profiles and prognoses. MYC gene family members are often overexpressed and/or amplified in all MB s...

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Publié dans:Neuro Oncol
Auteurs principaux: Čančer, Matko, Hutter, Sonja, Rosén, Gabriela, Hellström, Ann-Charlotte, Essand, Magnus, Huang, Miller, Tailor, Jignesh, Smith, Austin, Weiss, William A, Falk, Anna, Weishaupt, Holger, Swartling, Fredrik
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2017
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Abstracts
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692857/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.1044
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