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MBRS-42. GMYC: A NOVEL INDUCIBLE TRANSGENIC MODEL OF GROUP 3 MEDULLOBLASTOMA
Group 3 medulloblastoma (MB) carry the worst prognosis of all MB. The transcription factors MYC and MYCN have been suggested as drivers for a subset of these tumors, with MYC amplifications (17-20%) representing the most common genetic alteration in Group 3 tumors, while MYCN amplifications (4-6%) a...
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| Publié dans: | Neuro Oncol |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6012900/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.487 |
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