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ATRT-15. TARGETING LIN28 REGULATED PATHWAYS IN NOVEL THERAPEUTICS DEVELOPMENT FOR CNS ATYPICAL TERATOID/RHABDOID TUMOR (CNS ATRT)
INTRODUCTION: Elevated levels of LIN28A expression in AT/RT samples provide the rationale to search for agents that may interfere with cellular pathways regulated by this molecule. Ornithine decarboxylase (ODC) modulates eIF-5A through polyamines production and has been shown to directly influence t...
Na minha lista:
| Foilsithe in: | Neuro Oncol |
|---|---|
| Main Authors: | , , , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
Oxford University Press
2019
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6477221/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.013 |
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