ATRT-15. TARGETING LIN28 REGULATED PATHWAYS IN NOVEL THERAPEUTICS DEVELOPMENT FOR CNS ATYPICAL TERATOID/RHABDOID TUMOR (CNS ATRT)

INTRODUCTION: Elevated levels of LIN28A expression in AT/RT samples provide the rationale to search for agents that may interfere with cellular pathways regulated by this molecule. Ornithine decarboxylase (ODC) modulates eIF-5A through polyamines production and has been shown to directly influence t...

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Detaylı Bibliyografya
Yayımlandı:Neuro Oncol
Asıl Yazarlar: Kannappan, Sunand, Gupta, Mehul, Zhang, Chunfen, Hofmann, Bradley, Chi, Susan, Hanson, Derek, Narendran, Aru
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2019
Konular:
Atypical Teratoid Rhabdoid Tumor (ATRT)
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477221/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.013
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