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THER-11. BMI-1 MODULATION IMPAIRS DNA DAMAGE RESPONSE AND SENSITIZES DIPG CELLS TO IONIZING RADIATION
Diffuse intrinsic pontine glioma (DIPG) is a poor-prognosis brain tumor with no effective curative therapy. We previously identified BMI-1 as a potential therapeutic target in DIPG*. We have shown that BMI-1 is highly expressed in DIPG tumors and patient-derived cells regardless of histone subtype....
Gorde:
| Argitaratua izan da: | Neuro Oncol |
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| Egile Nagusiak: | , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Oxford University Press
2019
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6477219/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.218 |
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