DIPG-18. VALIDATION OF BMI-1 AS A THERAPEUTIC TARGET IN DIFFUSE INTRINSIC PONTINE GLIOMA

Diffuse intrinsic pontine glioma (DIPG) is a poor-prognosis pediatric brain tumor. No effective curative therapy is currently available and no therapeutic advances have been made in several decades. BMI-1 is a member of the multimeric protein complex Polycomb repressor complex 1. It is overexpressed...

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Bibliographic Details
Published in:Neuro Oncol
Main Authors: Kumar, Shiva Senthil, Sengupta, Satarupa, Lee, Kyungwoo, Hura, Nanki, Drissi, Rachid
Format: Artigo
Language:Inglês
Published: Oxford University Press 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475011/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.033
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