DIPG-17. TELOMERE-INDUCED DAMAGE AS A NOVEL APPROACH TO TREAT DIFFUSE INTRINSIC PONTINE GLIOMA

Diffuse intrinsic pontine glioma (DIPG) is one of the deadliest brain tumors in children. Hence, there is an urgent need to identify actionable therapeutic targets. We have previously shown that over 70% of DIPGs demonstrate telomerase activity and elevated hTERT mRNA levels are associated with shor...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Sengupta, Satarupa, White, Angela R., Kumar, Shiva Senthil, Lee, Kyungwoo, Fuller, Christine, DeWire, Mariko, Fouladi, Maryam, Chow, Lionel M.L., Drissi, Rachid
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475007/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.032
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