DIPG-17. TELOMERE-INDUCED DAMAGE AS A NOVEL APPROACH TO TREAT DIFFUSE INTRINSIC PONTINE GLIOMA

Diffuse intrinsic pontine glioma (DIPG) is one of the deadliest brain tumors in children. Hence, there is an urgent need to identify actionable therapeutic targets. We have previously shown that over 70% of DIPGs demonstrate telomerase activity and elevated hTERT mRNA levels are associated with shor...

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Détails bibliographiques
Publié dans:Neuro Oncol
Auteurs principaux: Sengupta, Satarupa, White, Angela R., Kumar, Shiva Senthil, Lee, Kyungwoo, Fuller, Christine, DeWire, Mariko, Fouladi, Maryam, Chow, Lionel M.L., Drissi, Rachid
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2017
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Abstracts
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475007/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.032
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