DIPG-18. SONIC HEDGEHOG (SHH) SIGNALLING PROMOTES BLOOD BRAIN BARRIER (BBB) INTEGRITY IN DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)

DIPG is the most common brainstem tumor in children and is uniformly fatal. The BBB is intact in DIPG and plays an active role in restricting the delivery of systemically administered therapies into the tumor. Recent studies have shown that SHH signalling plays a major role in the maintenance of BBB...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Neuro Oncol
Autori principali: Sajesh, Babu, On, Ngoc, Donald, Miller, Kazina, Colin, Serletis, Demitre, Del-Bigio, Marc, Krawitz, Sherry, Hulleman, Esther, Vanan, Magimairajan Issai
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
Soggetti:
Diffuse Intrinsic Pontine Glioma (DIPG)
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477213/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.039
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi