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Ancestral Stress Alters Lifetime Mental Health Trajectories and Cortical Neuromorphology via Epigenetic Regulation

Experiences during early development are powerful determinants of lifetime mental health. Here we investigated if ancestral stress regulates the brain’s epigenetic memory to alter neuromorphology and emotionality in the remote F4 progeny. Pregnant female rat dams of the parental F0 generation were e...

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Publicado en:Sci Rep
Main Authors: Ambeskovic, Mirela, Babenko, Olena, Ilnytskyy, Yaroslav, Kovalchuk, Igor, Kolb, Bryan, Metz, Gerlinde A. S.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6476877/
https://ncbi.nlm.nih.gov/pubmed/31011159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42691-z
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