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Immunosenescence is associated with altered gene expression and epigenetic regulation in primary and secondary immune organs

Deterioration of the immune system (immunosenescence) with age is associated with an increased susceptibility to infection, autoimmune disease and cancer, and reduced responsiveness to vaccination. Immunosenescence entails a reduced supply of naïve T cells from the thymus and increased specializatio...

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Detalhes bibliográficos
Main Authors: Sidler, Corinne, Wóycicki, Rafał, Ilnytskyy, Yaroslav, Metz, Gerlinde, Kovalchuk, Igor, Kovalchuk, Olga
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798808/
https://ncbi.nlm.nih.gov/pubmed/24151501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2013.00211
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