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Ancestral Stress Alters Lifetime Mental Health Trajectories and Cortical Neuromorphology via Epigenetic Regulation

Experiences during early development are powerful determinants of lifetime mental health. Here we investigated if ancestral stress regulates the brain’s epigenetic memory to alter neuromorphology and emotionality in the remote F4 progeny. Pregnant female rat dams of the parental F0 generation were e...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ambeskovic, Mirela, Babenko, Olena, Ilnytskyy, Yaroslav, Kovalchuk, Igor, Kolb, Bryan, Metz, Gerlinde A. S.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6476877/
https://ncbi.nlm.nih.gov/pubmed/31011159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42691-z
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