Ancestral exposure to stress epigenetically programs preterm birth risk and adverse maternal and newborn outcomes

BACKGROUND: Chronic stress is considered to be one of many causes of human preterm birth (PTB), but no direct evidence has yet been provided. Here we show in rats that stress across generations has downstream effects on endocrine, metabolic and behavioural manifestations of PTB possibly via microRNA...

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Detalhes bibliográficos
Publicado no:BMC Med
Main Authors: Yao, Youli, Robinson, Alexandra M, Zucchi, Fabiola CR, Robbins, Jerrah C, Babenko, Olena, Kovalchuk, Olga, Kovalchuk, Igor, Olson, David M, Metz, Gerlinde AS
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244860/
https://ncbi.nlm.nih.gov/pubmed/25286408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12916-014-0121-6
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