Ancestral exposure to stress epigenetically programs preterm birth risk and adverse maternal and newborn outcomes

BACKGROUND: Chronic stress is considered to be one of many causes of human preterm birth (PTB), but no direct evidence has yet been provided. Here we show in rats that stress across generations has downstream effects on endocrine, metabolic and behavioural manifestations of PTB possibly via microRNA...

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Publicat a:BMC Med
Autors principals: Yao, Youli, Robinson, Alexandra M, Zucchi, Fabiola CR, Robbins, Jerrah C, Babenko, Olena, Kovalchuk, Olga, Kovalchuk, Igor, Olson, David M, Metz, Gerlinde AS
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244860/
https://ncbi.nlm.nih.gov/pubmed/25286408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12916-014-0121-6
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