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Immunosenescence is associated with altered gene expression and epigenetic regulation in primary and secondary immune organs

Deterioration of the immune system (immunosenescence) with age is associated with an increased susceptibility to infection, autoimmune disease and cancer, and reduced responsiveness to vaccination. Immunosenescence entails a reduced supply of naïve T cells from the thymus and increased specializatio...

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Dettagli Bibliografici
Autori principali: Sidler, Corinne, Wóycicki, Rafał, Ilnytskyy, Yaroslav, Metz, Gerlinde, Kovalchuk, Igor, Kovalchuk, Olga
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798808/
https://ncbi.nlm.nih.gov/pubmed/24151501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2013.00211
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