Impeding the single-strand annealing pathway of DNA double-strand break repair by withaferin A-mediated FANCA degradation

FANCA is a key player in the canonical Fanconi anemia (FA) repair pathway. We have recently shown that FANCA also plays an important role in the single-strand annealing sub-pathway (SSA) of DNA double-strand break (DSB) repair by biochemically catalyzing single-strand annealing. Here, we report that...

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Detalhes bibliográficos
Publicado no:DNA Repair (Amst)
Main Authors: Liu, Wenjun, Wang, Guanying, Palovcak, Anna, Li, Yan, Hao, Sophie, Liu, Zhao-Jun, Landgraf, Ralf, Yuan, Fenghua, Zhang, Yanbin
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6476309/
https://ncbi.nlm.nih.gov/pubmed/30844655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2019.02.010
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