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Stitching up broken DNA ends by FANCA

RAD52 rejoins resected broken DNA ends by mediating single-strand annealing. Our recent work elucidates that FANCA, a Fanconi anemia protein, also directly repairs double-strand breaks (DSBs) by catalyzing annealing of single-stranded DNA. FANCA and RAD52 likely play complementary roles to each othe...

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Bibliografiske detaljer
Udgivet i:Mol Cell Oncol
Main Authors: Palovcak, Anna, Liu, Wenjun, Yuan, Fenghua, Zhang, Yanbin
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6276842/
https://ncbi.nlm.nih.gov/pubmed/30525096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2018.1518101
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