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Maintenance of genome stability by Fanconi anemia proteins

Persistent dysregulation of the DNA damage response and repair in cells causes genomic instability. The resulting genetic changes permit alterations in growth and proliferation observed in virtually all cancers. However, an unstable genome can serve as a double-edged sword by providing survival adva...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell Biosci
Hauptverfasser: Palovcak, Anna, Liu, Wenjun, Yuan, Fenghua, Zhang, Yanbin
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5320776/
https://ncbi.nlm.nih.gov/pubmed/28239445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-016-0134-2
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