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Impeding the single-strand annealing pathway of DNA double-strand break repair by withaferin A-mediated FANCA degradation
FANCA is a key player in the canonical Fanconi anemia (FA) repair pathway. We have recently shown that FANCA also plays an important role in the single-strand annealing sub-pathway (SSA) of DNA double-strand break (DSB) repair by biochemically catalyzing single-strand annealing. Here, we report that...
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| Udgivet i: | DNA Repair (Amst) |
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| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6476309/ https://ncbi.nlm.nih.gov/pubmed/30844655 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2019.02.010 |
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