CA Mutation N57A Has Distinct Strain-Specific HIV-1 Capsid Uncoating and Infectivity Phenotypes

The ability of human immunodeficiency virus type 1 (HIV-1) to transduce nondividing cells is key to infecting terminally differentiated macrophages, which can serve as a long-term reservoir of HIV-1 infection. The mutation N57A in the viral CA protein renders HIV-1 cell cycle dependent, allowing exa...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Fischer, Douglas K., Saito, Akatsuki, Kline, Christopher, Cohen, Romy, Watkins, Simon C., Yamashita, Masahiro, Ambrose, Zandrea
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2019
Fag:
Virus-Cell Interactions
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6475785/
https://ncbi.nlm.nih.gov/pubmed/30814280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00214-19
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