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Identification of Capsid Mutations That Alter the Rate of HIV-1 Uncoating in Infected Cells

After viral fusion with the cell membrane, the conical capsid of HIV-1 disassembles by a process called uncoating. We recently utilized the cyclosporine (CsA) washout assay, in which TRIM-CypA-mediated restriction of viral replication is used to detect the state of the viral capsid, to study the kin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Hulme, Amy E., Kelley, Z, Okocha, Eneniziaogochukwu A., Hope, Thomas J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301138/
https://ncbi.nlm.nih.gov/pubmed/25339776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03043-14
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