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Complementary Assays Reveal a Low Level of CA Associated with Viral Complexes in the Nuclei of HIV-1-Infected Cells

During uncoating, the conical capsid of HIV disassembles by dissociation of the p24 capsid protein (CA). Uncoating is known to be required for HIV replication, but the mechanism is poorly defined. Here, we examined the timing and effect of two capsid binding drugs (PF74 and BI2) on infectivity and c...

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Dades bibliogràfiques
Publicat a:J Virol
Autors principals: Hulme, Amy E., Kelley, Z, Foley, Deirdre, Hope, Thomas J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442523/
https://ncbi.nlm.nih.gov/pubmed/25741002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00476-15
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