Multiple Pathways To Avoid Beta Interferon Sensitivity of HIV-1 by Mutations in Capsid

Type I interferons (IFNs), including alpha IFN (IFN-α) and IFN-β, potently suppress HIV-1 replication by upregulating IFN-stimulated genes (ISGs). The viral capsid protein (CA) partly determines the sensitivity of HIV-1 to IFNs. However, it remains to be determined whether CA-related functions, incl...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Sultana, Tahmina, Mamede, João I., Saito, Akatsuki, Ode, Hirotaka, Nohata, Kyotaro, Cohen, Romy, Nakayama, Emi E., Iwatani, Yasumasa, Yamashita, Masahiro, Hope, Thomas J., Shioda, Tatsuo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6854511/
https://ncbi.nlm.nih.gov/pubmed/31511380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00986-19
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