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Effects of the nitric oxide synthase inhibitor ronopterin (VAS203) on renal function in healthy volunteers

AIMS: Reduced nitric oxide (NO) availability may adversely affect renal perfusion and glomerular filtration. The aim of the present study was to characterize in detail the pharmacological effects of VAS203, an inhibitor of NO synthase, on renal haemodynamics in humans. METHODS: This double‐blind, ra...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Br J Clin Pharmacol
Prif Awduron: Ott, Christian, Bosch, Agnes, Winzer, Nicole, Friedrich, Stephanie, Schinzel, Reinhard, Tegtmeier, Frank, Schmieder, Roland E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6475696/
https://ncbi.nlm.nih.gov/pubmed/30666700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13870
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