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Effects of the nitric oxide synthase inhibitor ronopterin (VAS203) on renal function in healthy volunteers

AIMS: Reduced nitric oxide (NO) availability may adversely affect renal perfusion and glomerular filtration. The aim of the present study was to characterize in detail the pharmacological effects of VAS203, an inhibitor of NO synthase, on renal haemodynamics in humans. METHODS: This double‐blind, ra...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Ott, Christian, Bosch, Agnes, Winzer, Nicole, Friedrich, Stephanie, Schinzel, Reinhard, Tegtmeier, Frank, Schmieder, Roland E.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6475696/
https://ncbi.nlm.nih.gov/pubmed/30666700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13870
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