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Effects of the nitric oxide synthase inhibitor ronopterin (VAS203) on renal function in healthy volunteers

AIMS: Reduced nitric oxide (NO) availability may adversely affect renal perfusion and glomerular filtration. The aim of the present study was to characterize in detail the pharmacological effects of VAS203, an inhibitor of NO synthase, on renal haemodynamics in humans. METHODS: This double‐blind, ra...

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Vydáno v:Br J Clin Pharmacol
Hlavní autoři: Ott, Christian, Bosch, Agnes, Winzer, Nicole, Friedrich, Stephanie, Schinzel, Reinhard, Tegtmeier, Frank, Schmieder, Roland E.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6475696/
https://ncbi.nlm.nih.gov/pubmed/30666700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13870
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