Effects of the nitric oxide synthase inhibitor ronopterin (VAS203) on renal function in healthy volunteers

AIMS: Reduced nitric oxide (NO) availability may adversely affect renal perfusion and glomerular filtration. The aim of the present study was to characterize in detail the pharmacological effects of VAS203, an inhibitor of NO synthase, on renal haemodynamics in humans. METHODS: This double‐blind, ra...

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Bibliographic Details
Published in:Br J Clin Pharmacol
Main Authors: Ott, Christian, Bosch, Agnes, Winzer, Nicole, Friedrich, Stephanie, Schinzel, Reinhard, Tegtmeier, Frank, Schmieder, Roland E.
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2019
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6475696/
https://ncbi.nlm.nih.gov/pubmed/30666700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13870
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