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Physiologically‐based pharmacokinetics of ziprasidone in pregnant women

AIMS: Pregnancy is associated with physiological changes that alter the pharmacokinetics (PK) of drugs. The aim of this study was to predict the PK of ziprasidone in pregnant women. METHODS: A full physiologically‐based pharmacokinetic (PBPK) model of ziprasidone was developed and validated for the...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Biesdorf, Carla, Martins, Frederico S., Sy, Sherwin K.B., Diniz, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6475689/
https://ncbi.nlm.nih.gov/pubmed/30669177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13872
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