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Physiologically-based pharmacokinetic modeling of renally excreted antiretroviral drugs in pregnant women
AIM: Physiological changes during pregnancy can affect drug disposition. Anticipating these changes will help to maximize drug efficacy and safety in pregnant women. Our objective was to determine if physiologically-based pharmacokinetics (PBPK) can accurately predict changes in the disposition of r...
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| Опубликовано в: : | Br J Clin Pharmacol |
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| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
John Wiley & Sons, Ltd
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4631176/ https://ncbi.nlm.nih.gov/pubmed/26011128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12685 |
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