Maternal and fetal zidovudine pharmacokinetics during pregnancy and labour: too high dose infused at labour?

AIMS: The main goal of the study was to describe the pharmacokinetics of maternal zidovudine (ZDV) administration during pregnancy and labour and to evaluate their impact on fetal concentrations and exposures. METHODS: A total of 195 HIV-infected pregnant and non-pregnant women aged 16–59 years were...

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Dettagli Bibliografici
Pubblicato in:Br J Clin Pharmacol
Autori principali: Fauchet, Floris, Treluyer, Jean-Marc, Valade, Elodie, Benaboud, Sihem, Pannier, Emmanuelle, Firtion, Ghislaine, Foissac, Frantz, Bouazza, Naim, Urien, Saik, Hirt, Déborah
Natura: Artigo
Lingua:Inglês
Pubblicazione: BlackWell Publishing Ltd 2014
Soggetti:
Pharmacokinetics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256627/
https://ncbi.nlm.nih.gov/pubmed/25040510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12459
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