A Novel Dopamine D1 Receptor Agonist Excites Delay-Dependent Working Memory-Related Neuronal Firing in Primate Dorsolateral Prefrontal Cortex

Decades of research have emphasized the importance of dopamine (DA) D1 receptor (D1R) mechanisms to dorsolateral prefrontal cortex (dlPFC) working memory function, and the hope that D1R agonists could be used to treat cognitive disorders. However, existing D1R agonists all have had high affinity for...

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發表在:Neuropharmacology
Main Authors: Wang, Min, Datta, Dibyadeep, Enwright, John, Galvin, Veronica, Yang, Sheng-Tao, Paspalas, Constantinos, Kozak, Rouba, Gray, David L., Lewis, David A., Arnsten, Amy F.T.
格式: Artigo
語言:Inglês
出版: 2019
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6475613/
https://ncbi.nlm.nih.gov/pubmed/30858103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2019.03.001
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