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Successive Nucleophilic and Electrophilic Allylation for The Catalytic Enantioselective Synthesis of 2,4-Disubstituted Pyrrolidines
Successive nucleophilic and electrophilic allylation mediated by the bis-Boc-carbonate derived from 2-methylene−1,3-propane diol enables formation of enantiomerically enriched 2,4-disubstituted pyrrolidines. An initial enantioselective iridium-catalyzed transfer hydrogenative carbonyl C-allylation i...
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| Publicado no: | Org Lett |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6475487/ https://ncbi.nlm.nih.gov/pubmed/30816719 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.9b00508 |
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