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Catalytic Enantioselective Allylic Amination of Olefins for the Synthesis of ent-Sitagliptin

The presence of nitrogen atoms in most chiral pharmaceutical drugs has motivated the development of numerous strategies for the synthesis of enantioenriched amines. Current methods are based on the multi-step transformation of pre-functionalized allylic electrophiles into chiral allylic amines. The...

詳細記述

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書誌詳細
出版年:Synlett
主要な著者: Bao, Hongli, Bayeh, Liela, Tambar, Uttam K.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4219538/
https://ncbi.nlm.nih.gov/pubmed/25378809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0033-1340079
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