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Catalytic Enantioselective Allylic Amination of Olefins for the Synthesis of ent-Sitagliptin
The presence of nitrogen atoms in most chiral pharmaceutical drugs has motivated the development of numerous strategies for the synthesis of enantioenriched amines. Current methods are based on the multi-step transformation of pre-functionalized allylic electrophiles into chiral allylic amines. The...
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| Publicat a: | Synlett |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4219538/ https://ncbi.nlm.nih.gov/pubmed/25378809 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0033-1340079 |
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