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Regio- and Enantioselective Iridium-Catalyzed Amination of Racemic Branched Alkyl-Substituted Allylic Acetates with Primary and Secondary Aromatic and Heteroaromatic Amines

The air and water stable π-allyliridium C,O-benzoate modified by (S)-tol-BINAP, (S)-Ir-II, catalyzes highly regio- and enantioselective Tsuji-Trost type aminations of racemic branched alkyl-substituted allylic acetates using primary or secondary (hetero)aromatic amines. Specifically, in the presence...

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Publicat a:J Am Chem Soc
Autors principals: Kim, Seung Wook, Schwartz, Leyah A., Zbieg, Jason R., Stivala, Craig E., Krische, Michael J.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6475470/
https://ncbi.nlm.nih.gov/pubmed/30571092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b12152
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