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Regio- and Enantioselective Iridium-Catalyzed N-Allylation of Indoles and Related Azoles with Racemic Branched Alkyl-Substituted Allylic Acetates

Rough, Ready and Regioselective. Stable to air, water and SiO(2), cyclometallated π-allyliridium C,O-benzoates modified by (S)-tol-BINAP catalyze highly enantioselective N-allylations of indoles and related azoles. Complementing the scope of all previously reported metal-catalyzed indole allylations...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Kim, Seung Wook, Schempp, Tabitha T., Zbieg, Jason R., Stivala, Craig E., Krische, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6534432/
https://ncbi.nlm.nih.gov/pubmed/30964961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201902799
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