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Colloidal Drug Aggregate Stability in High Serum Conditions and Pharmacokinetic Consequence

Colloidal drug aggregates have been a nuisance in drug screening, yet, because they inherently comprise drug-rich particles, they may be useful in vivo if issues of stability can be addressed. As the first step toward answering this question, we optimized colloidal drug aggregate formulations using...

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Bibliografiske detaljer
Udgivet i:ACS Chem Biol
Main Authors: Ganesh, Ahil N., Aman, Ahmed, Logie, Jennifer, Barthel, Ben L., Cogan, Peter, Al-awar, Rima, Koch, Tad H., Shoichet, Brian K., Shoichet, Molly S.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6474797/
https://ncbi.nlm.nih.gov/pubmed/30840432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.9b00032
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