Minocycline prevents nigrostriatal dopaminergic neurodegeneration in the MPTP model of Parkinson's disease

Parkinson's disease is a chronic neurodegenerative disorder characterized by the loss of dopamine neurons in the substantia nigra, decreased striatal dopamine levels, and consequent extrapyramidal motor dysfunction. We now report that minocycline, a semisynthetic tetracycline, recently shown to...

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Bibliografiske detaljer
Main Authors:	Du, Yansheng, Ma, Zhizhong, Lin, Suizhen, Dodel, Richard C., Gao, Feng, Bales, Kelly R., Triarhou, Lazarose C., Chernet, Eyassu, Perry, Ken W., Nelson, David L. G., Luecke, Susan, Phebus, Lee A., Bymaster, Frank P., Paul, Steven M.
Format:	Artigo
Sprog:	Inglês
Udgivet:	The National Academy of Sciences 2001
Fag:	Biological Sciences
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC64739/ https://ncbi.nlm.nih.gov/pubmed/11724929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.251341998
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Minocycline prevents nigrostriatal dopaminergic neurodegeneration in the MPTP model of Parkinson's disease

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