NPD-0414-2 and NPD-0414-24, Two Chemical Entities Designed as Aryl Hydrocarbon Receptor (AhR) Ligands, Inhibit Gut Inflammatory Signals

Defects in counterregulatory mechanisms contribute to amplify the detrimental inflammatory response leading to the pathologic process occurring in the gut of patients with Crohn’s disease (CD) and ulcerative colitis (UC), the major inflammatory bowel diseases (IBDs), in human beings. One such mechan...

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Vydáno v:Front Pharmacol
Hlavní autoři: Marafini, Irene, Di Fusco, Davide, Dinallo, Vincenzo, Franzè, Eleonora, Stolfi, Carmine, Sica, Giuseppe, Monteleone, Giovanni, Monteleone, Ivan
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6473199/
https://ncbi.nlm.nih.gov/pubmed/31031628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00380
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