NPD-0414-2 and NPD-0414-24, Two Chemical Entities Designed as Aryl Hydrocarbon Receptor (AhR) Ligands, Inhibit Gut Inflammatory Signals

Defects in counterregulatory mechanisms contribute to amplify the detrimental inflammatory response leading to the pathologic process occurring in the gut of patients with Crohn’s disease (CD) and ulcerative colitis (UC), the major inflammatory bowel diseases (IBDs), in human beings. One such mechan...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Marafini, Irene, Di Fusco, Davide, Dinallo, Vincenzo, Franzè, Eleonora, Stolfi, Carmine, Sica, Giuseppe, Monteleone, Giovanni, Monteleone, Ivan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6473199/
https://ncbi.nlm.nih.gov/pubmed/31031628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00380
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