NPD-0414-2 and NPD-0414-24, Two Chemical Entities Designed as Aryl Hydrocarbon Receptor (AhR) Ligands, Inhibit Gut Inflammatory Signals

Defects in counterregulatory mechanisms contribute to amplify the detrimental inflammatory response leading to the pathologic process occurring in the gut of patients with Crohn’s disease (CD) and ulcerative colitis (UC), the major inflammatory bowel diseases (IBDs), in human beings. One such mechan...

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Bibliografiske detaljer
Udgivet i:Front Pharmacol
Main Authors: Marafini, Irene, Di Fusco, Davide, Dinallo, Vincenzo, Franzè, Eleonora, Stolfi, Carmine, Sica, Giuseppe, Monteleone, Giovanni, Monteleone, Ivan
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6473199/
https://ncbi.nlm.nih.gov/pubmed/31031628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00380
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