NPD-0414-2 and NPD-0414-24, Two Chemical Entities Designed as Aryl Hydrocarbon Receptor (AhR) Ligands, Inhibit Gut Inflammatory Signals

Defects in counterregulatory mechanisms contribute to amplify the detrimental inflammatory response leading to the pathologic process occurring in the gut of patients with Crohn’s disease (CD) and ulcerative colitis (UC), the major inflammatory bowel diseases (IBDs), in human beings. One such mechan...

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Bibliografiska uppgifter
I publikationen:Front Pharmacol
Huvudupphovsmän: Marafini, Irene, Di Fusco, Davide, Dinallo, Vincenzo, Franzè, Eleonora, Stolfi, Carmine, Sica, Giuseppe, Monteleone, Giovanni, Monteleone, Ivan
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2019
Ämnen:
Pharmacology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6473199/
https://ncbi.nlm.nih.gov/pubmed/31031628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00380
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