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Dynamic filopodial forces induce accumulation, damage, and plastic remodeling of 3D extracellular matrices

The mechanical properties of the extracellular matrix (ECM)–a complex, 3D, fibrillar scaffold of cells in physiological environments–modulate cell behavior and can drive tissue morphogenesis, regeneration, and disease progression. For simplicity, it is often convenient to assume these properties to...

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Pubblicato in:PLoS Comput Biol
Autori principali: Malandrino, Andrea, Trepat, Xavier, Kamm, Roger D., Mak, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6472805/
https://ncbi.nlm.nih.gov/pubmed/30958816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006684
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