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Filopodial retraction force is generated by cortical actin dynamics and controlled by reversible tethering at the tip

Filopodia are dynamic, finger-like plasma membrane protrusions that sense the mechanical and chemical surroundings of the cell. Here, we show in epithelial cells that the dynamics of filopodial extension and retraction are determined by the difference between the actin polymerization rate at the tip...

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Detalhes bibliográficos
Main Authors: Bornschlögl, Thomas, Romero, Stéphane, Vestergaard, Christian L., Joanny, Jean-François, Van Nhieu, Guy Tran, Bassereau, Patricia
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3839779/
https://ncbi.nlm.nih.gov/pubmed/24198333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1316572110
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